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The nematode α-catenin ortholog, HMP1, has an extended α-helix when bound to actin filaments

The regulation of cell–cell junctions during epidermal morphogenesis ensures tissue integrity, a process regulated by α-catenin. This cytoskeletal protein connects the cadherin complex to filamentous actin at cell–cell junctions. The cadherin–catenin complex plays key roles in cell physiology, organ...

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Detalles Bibliográficos
Autores principales: Rangarajan, Erumbi S., Smith, Emmanuel W., Izard, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860117/
https://www.ncbi.nlm.nih.gov/pubmed/36539037
http://dx.doi.org/10.1016/j.jbc.2022.102817