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Measurements of Na(+)-occluded intermediates during the catalytic cycle of the Na(+)/K(+)-ATPase provide novel insights into the mechanism of Na(+) transport
The Na(+)/K(+)-ATPase is an integral plasma membrane glycoprotein of all animal cells that couples the exchange of intracellular Na(+) for extracellular K(+) to the hydrolysis of ATP. The asymmetric distribution of Na(+) and K(+) is essential for cellular life and constitutes the physical basis of a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860123/ https://www.ncbi.nlm.nih.gov/pubmed/36539036 http://dx.doi.org/10.1016/j.jbc.2022.102811 |