Measurements of Na(+)-occluded intermediates during the catalytic cycle of the Na(+)/K(+)-ATPase provide novel insights into the mechanism of Na(+) transport

The Na(+)/K(+)-ATPase is an integral plasma membrane glycoprotein of all animal cells that couples the exchange of intracellular Na(+) for extracellular K(+) to the hydrolysis of ATP. The asymmetric distribution of Na(+) and K(+) is essential for cellular life and constitutes the physical basis of a...

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Detalles Bibliográficos
Autores principales: Faraj, Santiago E., Valsecchi, Wanda M., Ferreira-Gomes, Mariela, Centeno, Mercedes, Saint Martin, Elina Malén, Fedosova, Natalya U., Rossi, Juan Pablo FC., Montes, Mónica R., Rossi, Rolando C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860123/
https://www.ncbi.nlm.nih.gov/pubmed/36539036
http://dx.doi.org/10.1016/j.jbc.2022.102811

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