Cargando…

Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures

Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the human brain. Here we investigated whether neuronal cultures derived from human induced pluripotent stem cells (hiPSCs) feature k...

Descripción completa

Detalles Bibliográficos
Autores principales: Estévez-Priego, Estefanía, Moreno-Fina, Martina, Monni, Emanuela, Kokaia, Zaal, Soriano, Jordi, Tornero, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860124/
https://www.ncbi.nlm.nih.gov/pubmed/36563684
http://dx.doi.org/10.1016/j.stemcr.2022.11.014