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Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures
Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the human brain. Here we investigated whether neuronal cultures derived from human induced pluripotent stem cells (hiPSCs) feature k...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860124/ https://www.ncbi.nlm.nih.gov/pubmed/36563684 http://dx.doi.org/10.1016/j.stemcr.2022.11.014 |