Systematic analyses of the sequence conservation and ligand interaction patterns of purinergic P1 and P2Y receptors provide a structural basis for receptor selectivity

Purinergic receptors are membrane proteins that regulate numerous cellular functions by catalyzing reactions involving purine nucleotides or nucleosides. Among the three receptor families, i.e., P1, P2X, and P2Y, the P1 and P2Y receptors share common structural features of class A GPCR. Comprehensiv...

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Detalles Bibliográficos
Autores principales: Han, Ri, Yoon, Hongryul, Yoo, Jiho, Lee, Yoonji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860165/
https://www.ncbi.nlm.nih.gov/pubmed/36698973
http://dx.doi.org/10.1016/j.csbj.2023.01.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860165/
https://www.ncbi.nlm.nih.gov/pubmed/36698973
http://dx.doi.org/10.1016/j.csbj.2023.01.010

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