Cargando…
Identification of transient intermediates during spliceosome activation by single molecule fluorescence microscopy
Spliceosome activation is the process of creating the catalytic site for RNA splicing and occurs de novo on each intron following spliceosome assembly. Dozens of factors bind to or are released from the activating spliceosome including the Lsm2-8 heteroheptameric ring that binds the U6 small nuclear...
Autores principales: | Fu, Xingyang, Kaur, Harpreet, Rodgers, Margaret L., Montemayor, Eric J., Butcher, Samuel E., Hoskins, Aaron A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860250/ https://www.ncbi.nlm.nih.gov/pubmed/36417433 http://dx.doi.org/10.1073/pnas.2206815119 |
Ejemplares similares
-
Single molecule analysis reveals reversible and irreversible steps during spliceosome activation
por: Hoskins, Aaron A, et al.
Publicado: (2016) -
Dynamics and consequences of spliceosome E complex formation
por: Larson, Joshua Donald, et al.
Publicado: (2017) -
Visualizing Single-molecule DNA Replication with Fluorescence Microscopy
por: Tanner, Nathan A., et al.
Publicado: (2009) -
Computational screen for spliceosomal RNA genes aids in defining the phylogenetic distribution of major and minor spliceosomal components
por: López, Marcela Dávila, et al.
Publicado: (2008) -
Structural bioinformatics of the human spliceosomal proteome
por: Korneta, Iga, et al.
Publicado: (2012)