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Target recognition by RNase E RNA-binding domain AR2 drives sRNA decay in the absence of PNPase
The C-terminal domain (CTD) of the major endoribonuclease RNase E not only serves as a scaffold for the central RNA decay machinery in gram-negative bacteria but also mediates coupled degradation of small regulatory RNAs (sRNAs) and their cognate target transcripts following RNA chaperone Hfq–facili...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860253/ https://www.ncbi.nlm.nih.gov/pubmed/36409892 http://dx.doi.org/10.1073/pnas.2208022119 |