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Target recognition by RNase E RNA-binding domain AR2 drives sRNA decay in the absence of PNPase

The C-terminal domain (CTD) of the major endoribonuclease RNase E not only serves as a scaffold for the central RNA decay machinery in gram-negative bacteria but also mediates coupled degradation of small regulatory RNAs (sRNAs) and their cognate target transcripts following RNA chaperone Hfq–facili...

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Detalles Bibliográficos
Autores principales: Sinha, Dhriti, De Lay, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860253/
https://www.ncbi.nlm.nih.gov/pubmed/36409892
http://dx.doi.org/10.1073/pnas.2208022119