Synthetic nanobodies as tools to distinguish IgG Fc glycoforms

Protein glycosylation is a crucial mediator of biological functions and is tightly regulated in health and disease. However, interrogating complex protein glycoforms is challenging, as current lectin tools are limited by cross-reactivity while mass spectrometry typically requires biochemical purific...

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Detalles Bibliográficos
Autores principales: Kao, Kevin S., Gupta, Aaron, Zong, Guanghui, Li, Chao, Kerschbaumer, Isabell, Borghi, Sara, Achkar, Jacqueline M., Bournazos, Stylianos, Wang, Lai-Xi, Ravetch, Jeffrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860306/
https://www.ncbi.nlm.nih.gov/pubmed/36409896
http://dx.doi.org/10.1073/pnas.2212658119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860306/
https://www.ncbi.nlm.nih.gov/pubmed/36409896
http://dx.doi.org/10.1073/pnas.2212658119

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