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Manipulating polydispersity of lens β-crystallins using divalent cations demonstrates evidence of calcium regulation

Crystallins comprise the protein-rich tissue of the eye lens. Of the three most common vertebrate subtypes, β-crystallins exhibit the widest degree of polydispersity due to their complex multimerization properties in situ. While polydispersity enables precise packing densities across the concentrati...

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Detalles Bibliográficos
Autores principales: Bergman, Michael R., Deravi, Leila F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860307/
https://www.ncbi.nlm.nih.gov/pubmed/36417439
http://dx.doi.org/10.1073/pnas.2212051119