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Regulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1

The DEAH/RHA helicase Prp43 remodels protein–RNA complexes during pre-messenger RNA (mRNA) splicing and ribosome biogenesis. The helicase activity and ATP turnover are intrinsically low and become activated by G-patch (gp) factors in the specific cellular context. The gp motif connects the helicase...

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Detalles Bibliográficos
Autores principales: Enders, Marieke, Ficner, Ralf, Adio, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860317/
https://www.ncbi.nlm.nih.gov/pubmed/36409901
http://dx.doi.org/10.1073/pnas.2203567119