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Regulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1
The DEAH/RHA helicase Prp43 remodels protein–RNA complexes during pre-messenger RNA (mRNA) splicing and ribosome biogenesis. The helicase activity and ATP turnover are intrinsically low and become activated by G-patch (gp) factors in the specific cellular context. The gp motif connects the helicase...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860317/ https://www.ncbi.nlm.nih.gov/pubmed/36409901 http://dx.doi.org/10.1073/pnas.2203567119 |