CTLA-4 on thymic epithelial cells complements Aire for T cell central tolerance

Medullary thymic epithelial cells (mTECs) are essential for the establishment of T cell central tolerance. The transcription factor Aire plays a key role in this process, but other factors remain understudied. We found that a small population of mTECs expressed the coinhibitory receptor cytotoxic T...

Descripción completa

Detalles Bibliográficos
Autores principales: Michelson, Daniel A., Benoist, Christophe, Mathis, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860321/
https://www.ncbi.nlm.nih.gov/pubmed/36409920
http://dx.doi.org/10.1073/pnas.2215474119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860321/
https://www.ncbi.nlm.nih.gov/pubmed/36409920
http://dx.doi.org/10.1073/pnas.2215474119

Ejemplares similares