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Titin force in muscle cells alters lattice order, thick and thin filament protein formation
Skeletal muscle force production is increased at longer compared to shorter muscle lengths because of length-dependent priming of thick filament proteins in the contractile unit before contraction. Using small-angle X-ray diffraction in combination with a mouse model that specifically cleaves the st...
Autores principales: | Hessel, Anthony L., Ma, Weikang, Mazara, Nicole, Rice, Paige E., Nissen, Devin, Gong, Henry, Kuehn, Michel, Irving, Thomas, Linke, Wolfgang A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860331/ https://www.ncbi.nlm.nih.gov/pubmed/36409887 http://dx.doi.org/10.1073/pnas.2209441119 |
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