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Insertions and deletions mediated functional divergence of Rossmann fold enzymes

Nucleobase-containing coenzymes are hypothesized to be relics of an early RNA-based world that preceded the emergence of proteins. Despite the importance of coenzyme–protein synergisms, their emergence and evolution remain understudied. An excellent target to address this issue is the Rossmann fold,...

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Detalles Bibliográficos
Autores principales: Toledo-Patiño, Saacnicteh, Pascarelli, Stefano, Uechi, Gen-ichiro, Laurino, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860332/
https://www.ncbi.nlm.nih.gov/pubmed/36417431
http://dx.doi.org/10.1073/pnas.2207965119