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Insertions and deletions mediated functional divergence of Rossmann fold enzymes
Nucleobase-containing coenzymes are hypothesized to be relics of an early RNA-based world that preceded the emergence of proteins. Despite the importance of coenzyme–protein synergisms, their emergence and evolution remain understudied. An excellent target to address this issue is the Rossmann fold,...
Autores principales: | Toledo-Patiño, Saacnicteh, Pascarelli, Stefano, Uechi, Gen-ichiro, Laurino, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860332/ https://www.ncbi.nlm.nih.gov/pubmed/36417431 http://dx.doi.org/10.1073/pnas.2207965119 |
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