Rapid nuclear deadenylation of mammalian messenger RNA

Poly(A) tails protect RNAs from degradation and their deadenylation rates determine RNA stability. Although poly(A) tails are generated in the nucleus, deadenylation of tails has mostly been investigated within the cytoplasm. Here, we combined long-read sequencing with metabolic labeling, splicing i...

Descripción completa

Detalles Bibliográficos
Autores principales: Alles, Jonathan, Legnini, Ivano, Pacelli, Maddalena, Rajewsky, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860345/
https://www.ncbi.nlm.nih.gov/pubmed/36691625
http://dx.doi.org/10.1016/j.isci.2022.105878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860345/
https://www.ncbi.nlm.nih.gov/pubmed/36691625
http://dx.doi.org/10.1016/j.isci.2022.105878

Ejemplares similares