TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks

Transforming growth factor-β1 (TGF-β1) can suppress the activation, proliferation, and function of many T-cell subsets, protecting organisms from inflammatory and autoimmune disease caused by an overexuberant immune response. However, whether and how TGF-β1 regulates T-cell immunity in early vertebr...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Geng, Ming, Li, Kang, Gao, Haiyou, Jiao, Xinying, Ai, Kete, Wei, Xiumei, Yang, Jialong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860442/
https://www.ncbi.nlm.nih.gov/pubmed/36581209
http://dx.doi.org/10.1016/j.jbc.2022.102843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860442/
https://www.ncbi.nlm.nih.gov/pubmed/36581209
http://dx.doi.org/10.1016/j.jbc.2022.102843

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