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TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks
Transforming growth factor-β1 (TGF-β1) can suppress the activation, proliferation, and function of many T-cell subsets, protecting organisms from inflammatory and autoimmune disease caused by an overexuberant immune response. However, whether and how TGF-β1 regulates T-cell immunity in early vertebr...
Autores principales: | Zhang, Qian, Geng, Ming, Li, Kang, Gao, Haiyou, Jiao, Xinying, Ai, Kete, Wei, Xiumei, Yang, Jialong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860442/ https://www.ncbi.nlm.nih.gov/pubmed/36581209 http://dx.doi.org/10.1016/j.jbc.2022.102843 |
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