Cargando…

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

RING-between RING (RBR)-type ubiquitin (Ub) ligases (E3s) such as Parkin receive Ub from Ub-conjugating enzymes (E2s) in response to ligase activation. However, the specific E2s that transfer Ub to each RBR-type ligase are largely unknown because of insufficient methods for monitoring their interact...

Descripción completa

Detalles Bibliográficos
Autores principales: Hayashida, Ryota, Kikuchi, Reika, Imai, Kenichiro, Kojima, Waka, Yamada, Tatsuya, Iijima, Miho, Sesaki, Hiromi, Tanaka, Keiji, Matsuda, Noriyuki, Yamano, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860496/
https://www.ncbi.nlm.nih.gov/pubmed/36563856
http://dx.doi.org/10.1016/j.jbc.2022.102822