Influence of Lipid Composition of Cationic Liposomes 2X3-DOPE on mRNA Delivery into Eukaryotic Cells

The design of cationic liposomes for efficient mRNA delivery can significantly improve mRNA-based therapies. Lipoplexes based on polycationic lipid 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)-7,11,16,20-tetraazahexacosane tetrahydrochloride (2X3) and helper lipid 1,2-dioleoyl-sn-glycero-3-phosphoet...

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Detalles Bibliográficos
Autores principales: Vysochinskaya, Vera, Shishlyannikov, Sergey, Zabrodskaya, Yana, Shmendel, Elena, Klotchenko, Sergey, Dobrovolskaya, Olga, Gavrilova, Nina, Makarova, Darya, Plotnikova, Marina, Elpaeva, Ekaterina, Gorshkov, Andrey, Moshkoff, Dmitry, Maslov, Mikhail, Vasin, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860636/
https://www.ncbi.nlm.nih.gov/pubmed/36678637
http://dx.doi.org/10.3390/pharmaceutics15010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860636/
https://www.ncbi.nlm.nih.gov/pubmed/36678637
http://dx.doi.org/10.3390/pharmaceutics15010008

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