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Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Study of New Benzotriazole-Based Bis-Schiff Base Derivatives

This study was carried out to synthesize benzotriazole-based bis-Schiff base scaffolds (1–20) and assess them in vitro for α-glucosidase inhibitory potentials. All the synthetics analogs based on benzotriazole-based bis-Schiff base scaffolds were found to display an outstanding inhibition profile on...

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Detalles Bibliográficos
Autores principales: Khan, Imran, Rehman, Wajid, Rahim, Fazal, Hussain, Rafaqat, Khan, Shoaib, Fazil, Srosh, Rasheed, Liaqat, Taha, Muhammad, Shah, Syed Adnan Ali, Abdellattif, Magda H., Farghaly, Thoraya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860641/
https://www.ncbi.nlm.nih.gov/pubmed/36678514
http://dx.doi.org/10.3390/ph16010017