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Cofactor Engineering for Efficient Production of α-Farnesene by Rational Modification of NADPH and ATP Regeneration Pathway in Pichia pastoris

α-Farnesene, an acyclic volatile sesquiterpene, plays important roles in aircraft fuel, food flavoring, agriculture, pharmaceutical and chemical industries. Here, by re-creating the NADPH and ATP biosynthetic pathways in Pichia pastoris, we increased the production of α-farnesene. First, the native...

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Detalles Bibliográficos
Autores principales: Chen, Sheng-Ling, Liu, Ting-Shan, Zhang, Wei-Guo, Xu, Jian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860691/
https://www.ncbi.nlm.nih.gov/pubmed/36675279
http://dx.doi.org/10.3390/ijms24021767