Cargando…

Cofactor Engineering for Efficient Production of α-Farnesene by Rational Modification of NADPH and ATP Regeneration Pathway in Pichia pastoris

α-Farnesene, an acyclic volatile sesquiterpene, plays important roles in aircraft fuel, food flavoring, agriculture, pharmaceutical and chemical industries. Here, by re-creating the NADPH and ATP biosynthetic pathways in Pichia pastoris, we increased the production of α-farnesene. First, the native...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Sheng-Ling, Liu, Ting-Shan, Zhang, Wei-Guo, Xu, Jian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860691/ https://www.ncbi.nlm.nih.gov/pubmed/36675279 http://dx.doi.org/10.3390/ijms24021767

Ejemplares similares

Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris
por: Krainer, Florian W, et al.
Publicado: (2015)

Cofactor engineering improved CALB production in Pichia pastoris through heterologous expression of NADH oxidase and adenylate kinase
por: Jayachandran, Charumathi, et al.
Publicado: (2017)

Engineering the oleaginous yeast Yarrowia lipolytica for production of α-farnesene
por: Liu, Yinghang, et al.
Publicado: (2019)

Engineered Pichia pastoris for enhanced production of S-adenosylmethionine
por: Kamarthapu, Venu, et al.
Publicado: (2013)

Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System
por: Abdel-Hady, Gamal Nasser, et al.
Publicado: (2021)

ATP Sulfurylase is Essential for the Utilization of Sulfamate as a Sulfur Source in the Yeast Komagataella pastoris (syn. Pichia pastoris)
por: Linder, Tomas
Publicado: (2017)

Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis
por: Geier, Martina, et al.
Publicado: (2015)

Metabolic engineering of Pichia pastoris for production of isobutanol and isobutyl acetate
por: Siripong, Wiparat, et al.
Publicado: (2018)

Engineered Pichia pastoris production of fusaruside, a selective immunomodulator
por: Tian, Yuan, et al.
Publicado: (2019)

Metabolic Engineering of Pichia pastoris for the Production of Triacetic Acid Lactone
por: Feng, Linjuan, et al.
Publicado: (2023)

A Simplified and Efficient Process for Insulin Production in Pichia pastoris
por: Polez, Sulena, et al.
Publicado: (2016)

Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris
por: Cai, Peng, et al.
Publicado: (2021)

Continuous Cultivation as a Tool Toward the Rational Bioprocess Development With Pichia Pastoris Cell Factory
por: Nieto-Taype, Miguel Angel, et al.
Publicado: (2020)

Engineered Production of Isobutanol from Sugarcane Trash Hydrolysates in Pichia pastoris
por: Bumrungtham, Pornsiri, et al.
Publicado: (2022)

Advances in Metabolic Engineering of Pichia pastoris Strains as Powerful Cell Factories
por: Zha, Jian, et al.
Publicado: (2023)

Modification of SARS-CoV S1 gene render expression in Pichia pastoris
por: Lu, Haisong, et al.
Publicado: (2006)

Development of quantitative metabolomics for Pichia pastoris
por: Carnicer, Marc, et al.
Publicado: (2011)

Expression of lignocellulolytic enzymes in Pichia pastoris
por: Mellitzer, Andrea, et al.
Publicado: (2012)

Dynamics in bioprocess development for Pichia pastoris
por: Spadiut, Oliver, et al.
Publicado: (2014)

Comparative genomics and transcriptomics of Pichia pastoris
por: Love, Kerry R., et al.
Publicado: (2016)

Synthetic Core Promoters for Pichia pastoris
por: Vogl, Thomas, et al.
Publicado: (2013)

Autolysis of Pichia pastoris induced by cold
por: Bartolo-Aguilar, Yaneth, et al.
Publicado: (2017)

An improved CRISPRi system in Pichia pastoris
por: Qiao, Shujing, et al.
Publicado: (2023)

Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris
por: Sygmund, Christoph, et al.
Publicado: (2011)

Construction of efficient xylose utilizing Pichia pastoris for industrial enzyme production
por: Li, Pengfei, et al.
Publicado: (2015)

Engineering a d-lactate dehydrogenase that can super-efficiently utilize NADPH and NADH as cofactors
por: Meng, Hengkai, et al.
Publicado: (2016)

Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway
por: Krainer, Florian W, et al.
Publicado: (2012)

Engineering Flocculation for Improved Tolerance and Production of d-Lactic Acid in Pichia pastoris
por: Sae-Tang, Kittapong, et al.
Publicado: (2023)

Upscale of recombinant α-L-rhamnosidase production by Pichia pastoris Mut(S) strain
por: Markošová, Kristína, et al.
Publicado: (2015)

Improving the Secretory Expression of an α-Galactosidase from Aspergillus niger in Pichia pastoris
por: Zheng, Xianliang, et al.
Publicado: (2016)

Cloning, expression, and characterization of a porcine pancreatic α-amylase in Pichia pastoris
por: Sun, Lv-hui, et al.
Publicado: (2018)

Production of Chimeric Acidic α-Amylase by the Recombinant Pichia pastoris and Its Applications
por: Parashar, Deepak, et al.
Publicado: (2017)

Overexpression of the riboflavin biosynthetic pathway in Pichia pastoris
por: Marx, Hans, et al.
Publicado: (2008)

Applications of recombinant Pichia pastoris in the healthcare industry
por: Weinacker, Daniel, et al.
Publicado: (2014)

Erratum to: Comparative genomics and transcriptomics of Pichia pastoris
por: Love, Kerry R., et al.
Publicado: (2016)

Production of protein-based polymers in Pichia pastoris
por: Werten, Marc W.T., et al.
Publicado: (2019)

Correction to: Autolysis of Pichia pastoris induced by cold
por: Bartolo-Aguilar, Yaneth, et al.
Publicado: (2018)

The effect of hypoxia on the lipidome of recombinant Pichia pastoris
por: Adelantado, Núria, et al.
Publicado: (2017)

Energy Charge as an Indicator of Pexophagy in Pichia pastoris
por: Zhang, Jianguo, et al.
Publicado: (2017)

Optimisation of Recombinant Myrosinase Production in Pichia pastoris
por: Rosenbergová, Zuzana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7ec8fk2gq1jgvfolhc95o5s0il