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Parent-Metabolite Pharmacokinetic Modeling of Formononetin and Its Active Metabolites in Rats after Oral Administration of Formononetin Formulations

Formononetin is a major isoflavone contained in propolis and is reported to exhibit various pharmacological effects. However, the use of formononetin in pharmaceutical industry is limited due to its low bioavailability and solubility. There had been several efforts on formononetin formulation develo...

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Detalles Bibliográficos
Autores principales: Kim, Ju Hee, Kang, Dong Wook, Cho, Seok-jin, Cho, Hea-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860708/
https://www.ncbi.nlm.nih.gov/pubmed/36678675
http://dx.doi.org/10.3390/pharmaceutics15010045