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Parent-Metabolite Pharmacokinetic Modeling of Formononetin and Its Active Metabolites in Rats after Oral Administration of Formononetin Formulations
Formononetin is a major isoflavone contained in propolis and is reported to exhibit various pharmacological effects. However, the use of formononetin in pharmaceutical industry is limited due to its low bioavailability and solubility. There had been several efforts on formononetin formulation develo...
Autores principales: | Kim, Ju Hee, Kang, Dong Wook, Cho, Seok-jin, Cho, Hea-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860708/ https://www.ncbi.nlm.nih.gov/pubmed/36678675 http://dx.doi.org/10.3390/pharmaceutics15010045 |
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