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Recrystallization Mediates the Gelation of Amorphous Drugs: The Case of Acemetacin

Amorphization is widely used as an effective method of increasing the solubility of insoluble drugs. However, some amorphous drugs exhibit a much lower dissolution rate than their corresponding crystalline form due to their gelation. In this study, we reported the gels formed from amorphous acemetac...

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Detalles Bibliográficos
Autores principales: Teng, Manlin, Li, Jianfeng, Li, Zhaohua, Zhang, Guangshuai, Zhao, Peixu, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860709/
https://www.ncbi.nlm.nih.gov/pubmed/36678848
http://dx.doi.org/10.3390/pharmaceutics15010219