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The Formation of RNA Pre-Polymers in the Presence of Different Prebiotic Mineral Surfaces Studied by Molecular Dynamics Simulations

We used all-atom Molecular Dynamics (MD) computer simulations to study the formation of pre-polymers between the four nucleotides in RNA (AMP, UMP, CMP, GMP) in the presence of different substrates that could have been present in a prebiotic environment. Pre-polymers are [Formula: see text] – [Formu...

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Detalles Bibliográficos
Autores principales: Dujardin, Alix, Himbert, Sebastian, Pudritz, Ralph, Rheinstädter, Maikel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860743/
https://www.ncbi.nlm.nih.gov/pubmed/36676060
http://dx.doi.org/10.3390/life13010112