Indene-Derived Hydrazides Targeting Acetylcholinesterase Enzyme in Alzheimer’s: Design, Synthesis, and Biological Evaluation

As acetylcholinesterase (AChE) plays a crucial role in advancing Alzheimer’s disease (AD), its inhibition is a promising approach for treating AD. Sulindac is an NSAID of the aryl alkanoic acid class, consisting of a indene moiety, which showed neuroprotective behavior in recent studies. In this stu...

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Detalles Bibliográficos
Autores principales: Gupta, Shraddha Manish, Behera, Ashok, Jain, Neetesh K., Kumar, Devendra, Tripathi, Avanish, Tripathi, Shailesh Mani, Mujwar, Somdutt, Patra, Jeevan, Negi, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860787/
https://www.ncbi.nlm.nih.gov/pubmed/36678724
http://dx.doi.org/10.3390/pharmaceutics15010094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860787/
https://www.ncbi.nlm.nih.gov/pubmed/36678724
http://dx.doi.org/10.3390/pharmaceutics15010094

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