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Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism

Hyperforin (HPF), the main component responsible for the antidepressant action of Hypericum perforatum, displays additional beneficial properties including anti-inflammatory, antimicrobic, and antitumor activities. Among its antitumor effects, HPF activity on melanoma is poorly documented. Melanoma,...

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Detalles Bibliográficos
Autores principales: Cardile, Alessia, Zanrè, Valentina, Campagnari, Rachele, Asson, Francesca, Addo, Solomon Saforo, Orlandi, Elisa, Menegazzi, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860844/
https://www.ncbi.nlm.nih.gov/pubmed/36674794
http://dx.doi.org/10.3390/ijms24021263