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Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism
Hyperforin (HPF), the main component responsible for the antidepressant action of Hypericum perforatum, displays additional beneficial properties including anti-inflammatory, antimicrobic, and antitumor activities. Among its antitumor effects, HPF activity on melanoma is poorly documented. Melanoma,...
Autores principales: | Cardile, Alessia, Zanrè, Valentina, Campagnari, Rachele, Asson, Francesca, Addo, Solomon Saforo, Orlandi, Elisa, Menegazzi, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860844/ https://www.ncbi.nlm.nih.gov/pubmed/36674794 http://dx.doi.org/10.3390/ijms24021263 |
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