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Effect of Double Mutation (L452R and E484Q) on the Binding Affinity of Monoclonal Antibodies (mAbs) against the RBD—A Target for Vaccine Development

The COVID-19 pandemic, caused by SARS-CoV-2, emerges as a global health problem, as the viral genome is evolving rapidly to form several variants. Advancement and progress in the development of effective vaccines and neutralizing monoclonal antibodies are promising to combat viral infections. In the...

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Detalles Bibliográficos
Autores principales: Gupta, Deepali, Kumar, Mukesh, Sharma, Priyanka, Mohan, Trishala, Prakash, Amresh, Kumari, Renu, Kaur, Punit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860914/
https://www.ncbi.nlm.nih.gov/pubmed/36679867
http://dx.doi.org/10.3390/vaccines11010023