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Pre-Transplant Total Lymphocyte Count Determines Anti-Thymocyte Globulin Exposure, Modifying Graft-versus-Host Disease Incidence and Post-Transplant Thymic Restoration: A Single-Center Retrospective Study

The use of anti-thymocyte globulin (ATG) as part of conditioning to prevent graft-versus-host disease (GVHD) may severely impair immune reconstitution (IR). We analyzed relationships between ATG exposure, the recipient lymphocyte count, IR, and transplant outcome. We retrospectively reviewed patient...

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Detalles Bibliográficos
Autores principales: Grasso, Antonio Giacomo, Simeone, Roberto, Maestro, Alessandra, Zanon, Davide, Maximova, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860924/
https://www.ncbi.nlm.nih.gov/pubmed/36675660
http://dx.doi.org/10.3390/jcm12020730