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Tumor-Infiltrating T Cells in EBV-Associated Gastric Carcinomas Exhibit High Levels of Multiple Markers of Activation, Effector Gene Expression, and Exhaustion

Epstein–Barr virus (EBV) is a gamma-herpesvirus associated with 10% of all gastric cancers (GCs) and 1.5% of all human cancers. EBV-associated GCs (EBVaGCs) are pathologically and clinically distinct entities from EBV-negative GCs (EBVnGCs), with EBVaGCs exhibiting differential molecular pathology,...

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Detalles Bibliográficos
Autores principales: Salnikov, Mikhail, Prusinkiewicz, Martin A., Lin, Sherman, Ghasemi, Farhad, Cecchini, Matthew J., Mymryk, Joe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860965/
https://www.ncbi.nlm.nih.gov/pubmed/36680216
http://dx.doi.org/10.3390/v15010176