In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents

Our previous study found that 2-phenyl-4-quinolone (2-PQ) derivatives are antimitotic agents, and we adopted the drug design concept of scaffold hopping to replace the 2-aromatic ring of 2-PQs with a 4-aromatic ring, representing 4-phenyl-2-quinolones (4-PQs). The 4-PQ compounds, whose structural ba...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Fong, Lawal, Bashir, Huang, Li-Jiau, Kuo, Sheng-Chu, Sumitra, Maryam Rachmawati, Mokgautsi, Ntlotlang, Lin, Hung-Yun, Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861105/
https://www.ncbi.nlm.nih.gov/pubmed/36677621
http://dx.doi.org/10.3390/molecules28020555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861105/
https://www.ncbi.nlm.nih.gov/pubmed/36677621
http://dx.doi.org/10.3390/molecules28020555

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