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Deciphering the Effect of Different Genetic Variants on Hippocampal Subfield Volumes in the General Population

The aim of this study was to disentangle the effects of various genetic factors on hippocampal subfield volumes using three different approaches: a biologically driven candidate gene approach, a hypothesis-free GWAS approach, and a polygenic approach, where AD risk alleles are combined with a polyge...

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Detalles Bibliográficos
Autores principales: Kirchner, Kevin, Garvert, Linda, Wittfeld, Katharina, Ameling, Sabine, Bülow, Robin, Meyer zu Schwabedissen, Henriette, Nauck, Matthias, Völzke, Henry, Grabe, Hans J., Van der Auwera, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861136/
https://www.ncbi.nlm.nih.gov/pubmed/36674637
http://dx.doi.org/10.3390/ijms24021120