Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer

Growth factors and cytokines released in the lung cancer microenvironment promote an epithelial-to-mesenchymal transition (EMT) that sustains the progression of neoplastic diseases. TGFβ is one of the most powerful inducers of this transition, as it induces overexpression of the fibronectin receptor...

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Detalles Bibliográficos
Autores principales: Andreucci, Elena, Bugatti, Kelly, Peppicelli, Silvia, Ruzzolini, Jessica, Lulli, Matteo, Calorini, Lido, Battistini, Lucia, Zanardi, Franca, Sartori, Andrea, Bianchini, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861180/
https://www.ncbi.nlm.nih.gov/pubmed/36674990
http://dx.doi.org/10.3390/ijms24021475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861180/
https://www.ncbi.nlm.nih.gov/pubmed/36674990
http://dx.doi.org/10.3390/ijms24021475

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