Tumor Treating Fields (TTFields) Induce Cell Junction Alterations in a Human 3D In Vitro Model of the Blood-Brain Barrier

In a recent study, we showed in an in vitro murine cerebellar microvascular endothelial cell (cerebEND) model as well as in vivo in rats that Tumor-Treating Fields (TTFields) reversibly open the blood–brain barrier (BBB). This process is facilitated by delocalizing tight junction proteins such as cl...

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Detalles Bibliográficos
Autores principales: Salvador, Ellaine, Köppl, Theresa, Hörmann, Julia, Schönhärl, Sebastian, Bugaeva, Polina, Kessler, Almuth F., Burek, Malgorzata, Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861254/
https://www.ncbi.nlm.nih.gov/pubmed/36678814
http://dx.doi.org/10.3390/pharmaceutics15010185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861254/
https://www.ncbi.nlm.nih.gov/pubmed/36678814
http://dx.doi.org/10.3390/pharmaceutics15010185

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