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Tumor Treating Fields (TTFields) Induce Cell Junction Alterations in a Human 3D In Vitro Model of the Blood-Brain Barrier
In a recent study, we showed in an in vitro murine cerebellar microvascular endothelial cell (cerebEND) model as well as in vivo in rats that Tumor-Treating Fields (TTFields) reversibly open the blood–brain barrier (BBB). This process is facilitated by delocalizing tight junction proteins such as cl...
Autores principales: | Salvador, Ellaine, Köppl, Theresa, Hörmann, Julia, Schönhärl, Sebastian, Bugaeva, Polina, Kessler, Almuth F., Burek, Malgorzata, Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861254/ https://www.ncbi.nlm.nih.gov/pubmed/36678814 http://dx.doi.org/10.3390/pharmaceutics15010185 |
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