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Improving Lurasidone Hydrochloride’s Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin

The biopharmaceutical classification system groups low-solubility drugs into two groups: II and IV, with high and low permeability, respectively. Most of the new drugs developed for common pathologies present solubility issues. This is the case of lurasidone hydrochloride—a drug used for the treatme...

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Detalles Bibliográficos
Autores principales: Gamboa-Arancibia, María Elena, Caro, Nelson, Gamboa, Alexander, Morales, Javier Octavio, González Casanova, Jorge Enrique, Rojas Gómez, Diana Marcela, Miranda-Rojas, Sebastián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861442/
https://www.ncbi.nlm.nih.gov/pubmed/36678861
http://dx.doi.org/10.3390/pharmaceutics15010232