Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury

Stroke is one of the leading causes of death. (D-ala2, D-leu5) enkephalin (DADLE) is a synthetic peptide and highly selective delta opioid receptor (δOR) agonist that has exhibited protective properties in ischemia. However, the specific target and mechanism are still unclear. The present study expl...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Chen, Meixuan, Deng, Zhongfang, Kong, Lingchao, Shen, Bing, Zhang, Lesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861451/
https://www.ncbi.nlm.nih.gov/pubmed/36678674
http://dx.doi.org/10.3390/pharmaceutics15010046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861451/
https://www.ncbi.nlm.nih.gov/pubmed/36678674
http://dx.doi.org/10.3390/pharmaceutics15010046

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