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Dental Pulp Inflammation Initiates the Occurrence of Mast Cells Expressing the α(1) and β(1) Subunits of Soluble Guanylyl Cyclase
The binding of nitric oxide (NO) to heme in the β(1) subunit of soluble guanylyl cyclase (sGC) activates both the heterodimeric α(1)β(1) and α(2)β(1) isoforms of the enzyme, leading to the increased production of cGMP from GTP. In cultured human mast cells, exogenous NO is able to inhibit mast cell...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861465/ https://www.ncbi.nlm.nih.gov/pubmed/36674416 http://dx.doi.org/10.3390/ijms24020901 |