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Endothelial Dysfunction Drives CRTd Outcome at 1-Year Follow-Up: A Novel Role as Biomarker for miR-130a-5p

Endothelial dysfunction (ED) causes worse prognoses in heart failure (HF) patients treated with cardiac resynchronization therapy (CRTd). ED triggers the downregulation of microRNA-130 (miR-130a-5p), which targets endothelin-1 (ET-1). Thus, we evaluated ED and the response to CRTd by assessing miR-1...

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Detalles Bibliográficos
Autores principales: Sardu, Celestino, Santulli, Gaetano, Savarese, Gianluigi, Trotta, Maria Consiglia, Sacra, Cosimo, Santamaria, Matteo, Volpicelli, Mario, Ruocco, Antonio, Mauro, Ciro, Signoriello, Giuseppe, Marfella, Lorenza, D’Amico, Michele, Marfella, Raffaele, Paolisso, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861580/
https://www.ncbi.nlm.nih.gov/pubmed/36675028
http://dx.doi.org/10.3390/ijms24021510