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TRPML1-Induced Lysosomal Ca(2+) Signals Activate AQP2 Translocation and Water Flux in Renal Collecting Duct Cells

Lysosomes are acidic Ca(2+) storage organelles that actively generate local Ca(2+) signaling events to regulate a plethora of cell functions. Here, we characterized lysosomal Ca(2+) signals in mouse renal collecting duct (CD) cells and we assessed their putative role in aquaporin 2 (AQP2)-dependent...

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Detalles Bibliográficos
Autores principales: Scorza, Simona Ida, Milano, Serena, Saponara, Ilenia, Certini, Maira, De Zio, Roberta, Mola, Maria Grazia, Procino, Giuseppe, Carmosino, Monica, Moccia, Francesco, Svelto, Maria, Gerbino, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861594/
https://www.ncbi.nlm.nih.gov/pubmed/36675161
http://dx.doi.org/10.3390/ijms24021647