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Advances in BBB on Chip and Application for Studying Reversible Opening of Blood–Brain Barrier by Sonoporation
The complex structure of the blood–brain barrier (BBB), which blocks nearly all large biomolecules, hinders drug delivery to the brain and drug assessment, thus decelerating drug development. Conventional in vitro models of BBB cannot mimic some crucial features of BBB in vivo including a shear stre...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861620/ https://www.ncbi.nlm.nih.gov/pubmed/36677173 http://dx.doi.org/10.3390/mi14010112 |