New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors

This paper reports an investigation into the impact of pyridyl functional groups in conjunction with hydroxide-substituted benzenesulfonamides on the inhibition of human carbonic anhydrase (CA; EC 4.2.1.1) enzymes. These compounds were tested in vitro of CA II and CA IX, two physiologically importan...

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Detalles Bibliográficos
Autores principales: Combs, Jacob, Bozdag, Murat, Cravey, Lochlin D., Kota, Anusha, McKenna, Robert, Angeli, Andrea, Carta, Fabrizio, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861757/
https://www.ncbi.nlm.nih.gov/pubmed/36677947
http://dx.doi.org/10.3390/molecules28020890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861757/
https://www.ncbi.nlm.nih.gov/pubmed/36677947
http://dx.doi.org/10.3390/molecules28020890

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