Stereoselective Synthesis and Antiproliferative Activities of Tetrafunctional Diterpene Steviol Derivatives

A new family of diterpene-type aminotriol derivatives has been synthesised from stevioside in a stereoselective manner. The key intermediate spiro-epoxide was prepared through the methyl ester of the allilyc diol derived from steviol. The oxirane ring was opened with primary and secondary amines, pr...

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Detalles Bibliográficos
Autores principales: Bai, Dorottya, Schelz, Zsuzsanna, Erdős, Dóra, Kis, Anna K., Nagy, Viktória, Zupkó, István, Balogh, György T., Szakonyi, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861858/
https://www.ncbi.nlm.nih.gov/pubmed/36674639
http://dx.doi.org/10.3390/ijms24021121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861858/
https://www.ncbi.nlm.nih.gov/pubmed/36674639
http://dx.doi.org/10.3390/ijms24021121

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