Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages

Orientia tsutsugamushi is an obligately intracellular bacterium and an etiological agent of scrub typhus. Human studies and animal models of scrub typhus have shown robust type 1-skewed proinflammatory responses during severe infection. Macrophages (MΦ) play a critical role in initiating such respon...

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Detalles Bibliográficos
Autores principales: Fisher, James, Gonzales, Casey, Chroust, Zachary, Liang, Yuejin, Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861896/
https://www.ncbi.nlm.nih.gov/pubmed/36678402
http://dx.doi.org/10.3390/pathogens12010053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861896/
https://www.ncbi.nlm.nih.gov/pubmed/36678402
http://dx.doi.org/10.3390/pathogens12010053

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