Cargando…
Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages
Orientia tsutsugamushi is an obligately intracellular bacterium and an etiological agent of scrub typhus. Human studies and animal models of scrub typhus have shown robust type 1-skewed proinflammatory responses during severe infection. Macrophages (MΦ) play a critical role in initiating such respon...
Autores principales: | Fisher, James, Gonzales, Casey, Chroust, Zachary, Liang, Yuejin, Soong, Lynn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861896/ https://www.ncbi.nlm.nih.gov/pubmed/36678402 http://dx.doi.org/10.3390/pathogens12010053 |
Ejemplares similares
-
Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice
por: Gonzales, Casey, et al.
Publicado: (2023) -
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
por: Liang, Yuejin, et al.
Publicado: (2022) -
Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice
por: Liang, Yuejin, et al.
Publicado: (2023) -
Scrub Typhus Pathogenesis: Innate Immune Response and Lung Injury During Orientia tsutsugamushi Infection
por: Trent, Brandon, et al.
Publicado: (2019) -
CCR7/dendritic cell axis mediates early bacterial dissemination in Orientia tsutsugamushi-infected mice
por: Liang, Yuejin, et al.
Publicado: (2022)